Howard M. Kipen, MD, MPH
Department of Environmental and Occupational Health
Air pollution; indoor air quality; biomarkers; cardiorespiratory effects of air pollution; multiple chemical sensitivities.
Dr. Kipen received his medical degree from UC San Francisco and his MPH from Columbia University. He trained in internal medicine at Columbia-Presbyterian and in occupational medicine at Mount Sinai Medical Center in NYC.
Dr. Kipen is interested in understanding health effects, and mechanisms, by which ambient air pollution and indoor air pollution produce those health effects. He leads experimental studies that increase or decrease short term levels of pollutant exposure and assesses resultant changes in respiratory and systemic oxidative stress.
Two hour drives on the New Jersey Turnpike lead to acute and reversible changes in respiratory and vascular biomarkers of oxidative stress.
Use of a portable air cleaner significantly reduces pollutant levels in urban homes in New Jersey.
Patton, A., Laumbach, R., Ohman-Strickland, P., Black, K., Alimokhtari, S., Lioy, P., Kipen, H. (2016) "Scripted drives: A robust protocol for generating exposures to traffic-related air pollution.", Atmospheric Environment (Oxford, England : 1994) Vol. 143 http://www.ncbi.nlm.nih.gov/pubmed/?term=27642251&report=abstract
Pettit, A., Kipen, H., Laumbach, R., Ohman-Strickland, P., Kelly-McNeill, K., Cepeda, C., Fan, Z., Amorosa, L., Lubitz, S., Schneider, S., Gow, A. (2015) "Disrupted Nitric Oxide Metabolism from Type II Diabetes and Acute Exposure to Particulate Air Pollution.", PloS one Vol. 10 http://www.ncbi.nlm.nih.gov/pubmed/?term=26656561&report=abstract
Laumbach, R., Kipen, H., Ko, S., Kelly-McNeil, K., Cepeda, C., Pettit, A., Ohman-Strickland, P., Zhang, L., Zhang, J., Gong, J., Veleeparambil, M., Gow, A. (2014) "A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability.", Particle and fibre toxicology Vol. 11 http://www.ncbi.nlm.nih.gov/pubmed/?term=25361615&report=abstract
Rich, D., Kipen, H., Huang, W., Wang, G., Wang, Y., Zhu, P., Ohman-Strickland, P., Hu, M., Philipp, C., Diehl, S., Lu, S., Tong, J., Gong, J., Thomas, D., Zhu, T., Zhang, J. (2012) "Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults.", JAMA Vol. 307 http://www.ncbi.nlm.nih.gov/pubmed/?term=22665106&report=abstract
Member, Planning Committee, Workshop on the Health Risks of Indoor Exposure to Particulate Matter National Academy of Sciences, Engineering, and Medic (2015)
Member, Board of Directors, American Thoracic Society (2017)
Member, National Academies Standing Committee on Medical and Epidemiological Aspects of Air Pollution on U.S. Government Employees and their Families (2016)
Chair of the American Thoracic Society Scientific Assembly on Environmental, Occupational, and Population Health