Environmental & Occupational Health

Faculty Profile

  • Howard M. Kipen, MD, MPH

  • Professor

  • Department of Environmental and Occupational Health

  • CV

Keywords
Air pollution; indoor air quality; biomarkers; cardiorespiratory effects of air pollution; multiple chemical sensitivities.

Biography
Dr. Kipen received his medical degree from UC San Francisco and his MPH from Columbia University. He trained in internal medicine at Columbia-Presbyterian and in occupational medicine at Mount Sinai Medical Center in NYC.

Research Interests
Dr. Kipen is interested in understanding health effects, and mechanisms, by which ambient air pollution and indoor air pollution produce those health effects. He leads experimental studies that increase or decrease short term levels of pollutant exposure and assesses resultant changes in respiratory and systemic oxidative stress.

Research Highlights

Two hour drives on the New Jersey Turnpike lead to acute and reversible changes in respiratory and vascular biomarkers of oxidative stress.

Use of a portable air cleaner significantly reduces pollutant levels in urban homes in New Jersey.

Select Publications
DQ Rich,HM Kipen,W Huang,G Wang,Y Wang,P Zhu,P Ohman-Strickland,M Hu,C Philipp,SR Diehl,SE Lu,J Tong,J Gong,D Thomas,T Zhu,JJ Zhang (2012) "Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults.", JAMA 307(5) 2068-2078 http://www.ncbi.nlm.nih.gov/pubmed/?term=22665106&report=abstract

RJ Laumbach,HM Kipen,S Ko,K Kelly-McNeil,C Cepeda,A Pettit,P Ohman-Strickland,L Zhang,J Zhang,J Gong,M Veleeparambil,AJ Gow (2014) "A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability.", Particle and fibre toxicology 11(5) 45- http://www.ncbi.nlm.nih.gov/pubmed/?term=25361615&report=abstract

AP Pettit,H Kipen,R Laumbach,P Ohman-Strickland,K Kelly-McNeill,C Cepeda,ZH Fan,L Amorosa,S Lubitz,S Schneider,A Gow (2015) "Disrupted Nitric Oxide Metabolism from Type II Diabetes and Acute Exposure to Particulate Air Pollution.", PloS one 10(5) - http://www.ncbi.nlm.nih.gov/pubmed/?term=26656561&report=abstract

AP Patton,R Laumbach,P Ohman-Strickland,K Black,S Alimokhtari,P Lioy,HM Kipen (2016) "Scripted drives: A robust protocol for generating exposures to traffic-related air pollution.", Atmospheric Environment (Oxford, England : 1994) 143(5) 290-299 http://www.ncbi.nlm.nih.gov/pubmed/?term=27642251&report=abstract

Scholarly Activities
Member, Planning Committee, Workshop on the Health Risks of Indoor Exposure to Particulate Matter National Academy of Sciences, Engineering, and Medic (2015)

Member, Board of Directors, American Thoracic Society (2017)

Member, National Academies Standing Committee on Medical and Epidemiological Aspects of Air Pollution on U.S. Government Employees and their Families (2016)

Chair of the American Thoracic Society Scientific Assembly on Environmental, Occupational, and Population Health